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ID 14422
Eprint ID
14422
FullText URL
Thumnail 103_993.pdf 3.48 MB
Title Alternative
Ultrastructural study of left ventricular myocardium in aortic regurgitation : Correlations with preoperative cardiac functions at rest
Author
Tsuji, Hisashi
Abstract
We collected tissue samples from the left ventricular myocardium in 20 patients with aortic regurgitation, examined the correlation between myocardial ultrastructure and cardiac function at rest and obtained the following results. The extent of fibrosis in the myocardium and ultrastructural changes in the myocardial cells were respectively expressed in LM-Score and EM-Score. Furthermore, the myofibril changes expressed by the EM-Score were added to the LM-Score (Myo+LM-Score), and each score was calculated and compared with the parameters of cardiac function. There was no significant correlation between EM-Score and parameters of cardiac function. LM-Score was correlated with Max dv/dt at r=-0.471 (p<0.05) and with endodiastole (D/L) at r=-0.567 (p<0.01) significantly, showing a negative linear correlation. Myo+LM-Score was correlated with EF at r=-0.574 (p<0.01) and with△ D at r=-0.577 (p<0.01) significantly, showing a negative linear correlation. Among the cardiac functions at rest in patients with AR, the morphologic and diastolic parameters were closely related with the extent of fibrosis, and the contractility was closely related both with a change in myofibrils and with the extent of fibrosis. Thus, the cardiac functions at rest in patients with AR were correlated with the myocardial factors.
Keywords
大動脈弁閉鎖不全症
安静時左心機能
心筋組織構造変化
Note
原著
Published Date
1991-08
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume103
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
993
End Page
1003
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/103/7-8/103_7-8_993/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma