このエントリーをはてなブックマークに追加
ID 14245
Eprint ID
14245
FullText URL
Thumnail 104_177.pdf 469 KB
Title Alternative
Treatment of small cell lung cancer in the elderly
Author
Hino, Norihiko
Abstract
To assess the progress and limitation of chemotherapy in the treatment of small cell lung cancer in the elderly, we analyzed 218 patients in a protocol study between 1982 and 1990. There were 101 elderly patients (age of ≧ 66 years) and 117 non-elderly patients (age of ≦ 65 years). Response to chemotherapy with or without chest irradiation was similar for the elderly and the non-elderly; the complete response rate was 52% for limited disease (LD) and 33% for extensive disease (ED) in the elderly, and it was 68% for LD and 23% for ED in the non-elderly. Survival figures of the two groups were similar; the median survival time was 12.6 monthes for the elderly and 14.5 months for the non-elderly, and the 3-year surival rate was 14% for both groups. Hematologic toxicity was more frequent and severe in the elderly than in the non-elderly but the difference was not significant. Non-hematologic toxicity was comparable for the two groups, with an exception that the elderly showed a tendency of being predisposed to renal toxicity. In conclusion, elderly patients eligible for entry into a protocol study can benefit from intensive treatment just as younger patients can.
Keywords
肺小細胞癌 Small cell lung cancer
老年者 Erderly patients
化学療法 Chemotherapy
副作用 Side effect
Published Date
1992
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume104
Issue
issue1-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
177
End Page
185
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/104/1-2/104_1-2_177/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma