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ID 13860
Eprint ID
13860
FullText URL
Title Alternative
Effects of fentanyl anesthesia on the canine excised cross-circulated heart preparation system
Author
Ishioka, Kazunari
Abstract
Sodium pentobarbital has been used as a representative anesthetic in the experimental system using the canine excised cross-circulated heart preparaton. In the present study, fentanyl was established as a new anesthetic in this experimental system. The mechanoenergetic effects of fentanyl on the excised heart were investigated by using the framework of Emax (the slope of the end-systolic pressure-volume relation), PVA (Pressure-volume area) and VO2 (left ventricle oxygen consumption per beat). To determine the effects of fentanyl on the support dog, the systemic arterial blood pressure, heart rate, and plasma catecholamine concentration were measured. In the excised heart, fentanyl did not change the slope of the PVA-VO2 relation. This indicated that the cardiac mechanoenergetics was not qualitatively changed by fentanyl. In the support dog, fentanyl decreased the heart rate, but did not change the systemic arterial blood pressure. Fentanyl anesthesia is considered to be useful as an anesthetic for the experimantal system using the canine excised cross-circulated heart preparation.
Keywords
麻薬
フェンタニール
Emax
PVA
酸素消費量
Note
原著
Published Date
1994-12
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume106
Issue
issue11-12
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1105
End Page
1116
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/106/11-12/106_11-12_1105/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma