このエントリーをはてなブックマークに追加
ID 13748
Eprint ID
13748
FullText URL
Thumnail 108_215.pdf 466 KB
Title Alternative
Serum levels of macrophage colony stimulating factor and other acute phase reactants after open heart surgery
Author
Chikakiyo, Hirokazu
Abstract
To clarify the phathophysiological role of macrophage colony stimulating factor (M-CSF) in the healing processes of inflammation, we studied chronological changes in serum concentrations of M-CSF and other reactants during the acute phase of inflammation in patients who underwent open heart surgery, since these patients showed a precise point of tissue damage. The number of neutrophilic leukocytes increased in the very early postoperative stage, reached a peak 48 h after surgery and declined to the basal level at day 14. The chronological changes in serum C-reactive protein level after surgery were similar to these of neutrophic leukocytes. Serum M-CSF concentrations increased gradually, reached a peak 7 days after surgery and remained at that level until day 14. Based on these phenomena, it is assumed that M-CSF plays a pathophysiological role in the healing processes of an inflammation. Measurement of the serum concentration of M-CSF would be useful for evaluating the process of inflammation.
Keywords
M-CSF
開心術
白血球数
急性相反応物質
サイトカイン
Note
原著
Published Date
1996-08-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume108
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
215
End Page
223
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/108/7-8/108_7-8_215/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma