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ID 13543
Eprint ID
13543
FullText URL
Thumnail 114_243.pdf 2.82 MB
Author
Kobayashi, Naoya
興津 輝
都津川 敏範
丸山 昌伸
小坂 芳和
荒田 尚司
小林 和也
野口 洋文
大橋 一郎
国枝 武美
柴田 憲邦
武居 道彦
尾下 瑞子
林 伸幸
中路 修平
大元 謙二
倉林 譲
山本 晋一郎
田中 紀章
Keywords
バイオ人工肝臓
不死化肝臓細胞
Cre/loxP 部位特異的組換え反応
reversible immortalization
Note
特別依頼原稿 ―岡山大学医学会賞(結城賞)を受賞して―
Published Date
2003-01-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume114
Issue
issue3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
243
End Page
251
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/114/3/114_3_243/_article/-char/ja/
References
1) Kobayashi N, Fujiwara T, Westerman KA, et al.: Prevention of acture liver failure in rats with reversibly immortalized human hepatocytes. Science(2000) 287, 1258.
2) Kobayashi N, et al.: Transplantation of highly differentiated immotralized human hepatocytes to treat acute liver failure. Transplantation (2000) 69, 202-207
3) Kobayashi N, et al.: Construction of a differentiated human hepatocyte cell line expressing the herpes simplex virus-thymidine kinase gene. ASAIO J.(2001) 47: 476-480.
4) Noguchi N, Kobayashi N, Westerman K.A,et al.: Controlled expansion of endothelial cell populations by Cre/loxP-based reversible ommotralization. Hum. Gene Ther. (2002) 13, 321
5) Kobayashi N, et al.: Rapidly functinal immobilization of immortalized human hepatocytes using cell adhesive GRGDS peptide-carrying cellulose microspheres. Cell Transplannt. (2001) 10, 387
6) Kobayshi N, Sakaguchi M, Okitsu T, et al.: Immprovement in the differentiated hepatic phenotype of immortalized human hepatocytes by adenovirus mediated p21 gene transfer. ASAIO J. (2002) 48, 355-359.
7) Kunieda T, N. Kobayashi, et al.: Cell Transplant. (in press).
8) Thomson JA, Itukovitz-Eldor J, Shapiro SS, et al.: Science (1998) 282, 1145
9) Lebkowski J, Gold J, Chiu, C-P, et al.: Human embryonic stem cells : defferentiation into cell types for transplantation applications. Cell Transplant. (2001) 10, 505.
10) Schwartz RE, Reyes M, Koodie L, et al.: Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J. Clin. Invest. (2002) 109, 1291-1302.
11) Sternberg N, Hamilton D.:Bacteriophage P1 site-specific recombination I. Recombination between loxP sites. J Mol Biol (1981) 150, 467.
12) Westerman KA, Leboulch P.: Reversible immortalization of mammalian cells mediated by retroviral transfer and site-specific recombination. Proc. Natl. Acad. Sci.(1996) 93, 8971.
13) Gatrner HV, Seidl C, Luckenbach G et al.: Genetic analysis of a sarcoma accidentally transplanted from a patient to a surgeon. New Eng. J. Med. (1996) 335, 1494.
14) Paradis K, Lamgford G, Long Z et al.: Search for cross-species transmission of porcine endogenous retrovirus in patient treated with living pig tissue. Science (1999) 285, 1236.
15) Bondar AG : Extension of life-span by introduction of telomerase into normal human cells. Science (1998) 279, 349.
16) Daewoong Jo, Nashabi A, Doxsee C, et al.: Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase. Nat. Biotech. (2001) 19, 929.
17) Harper JW, Adami GR, Wei N, et al.: The p21 Cdk-interacting protein Cip 1 is a potent inhibitor of G1 cyclin-dependent kinase. Cell (1993) 75, 805-816.
18) El-Deiry WS, Tokino T, Velculescu VE, et al.: WAF1, a potential mediator of p53 tumor suppression. Cell (1993) 75, 817-825.
19) Furuyama, A., Kimata, K ., and Mochitate, K.: Assembly of basement membrane in vitro by cooperation between alveolar epithelial cells and pulmonary fibroblasts, Cell Suruc. Func. (1997) 22, 603-614.
20) Grossmann M, Rader DJ, Muller DWM, et al.: A pilot study of ex vivo gene therapy for homologous familial hypercholeserolemia. Nature Medicine (1995) 1, 1148-1154.
21) Totsugawa T, Kobayashi N, Okitsu T, et al.: Lentiviral transfer of the lacZ gene into human endothelial cells and human bone marrow mesenchymal stem cells. Cell Transplant. (in press).
22) 都津川敏範,小林直哉,丸山昌伸ら:レンチウイルスベクターによるヒト血管内皮細胞への効果的な遺伝子導入,Organ biology (2001) 8, 277-285.
23) 丸山昌伸,小林直哉,都津川敏範ら:肝細胞へのレンチウイルスベクターを用いた遺伝子導入に関する基礎的研究. Organ Biology (in press).
language
日本語
OAI-PMH Set
岡山大学
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma