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ID 11818
Eprint ID
11818
FullText URL
Title Alternative
Alcoholic Liver Disease
Author
Endo, Hiroshi
Nakata, Yasunari
Mori, Shuji
Ohta, Takeo
Abstract
Relationship between ethanol drinking and organs injury was reviewed and special emphasis was put on alcoholic liver disease. Consumption of alcoholic beverage expressed as ethanol per capita of adult in Japan increased 2.1 times in these 25 years and it is still increasing. Although the incidence of alcoholic liver disease in Japan also increased greatly during the above period, it seems likely that plateau level is coming because of genetically defined, unique type of alcohol metabolism in Japanese. Sex differences in susceptibility to alcohol were discussed. Among the six types of alcoholic liver disease, alcoholic liver fibrosis is relatively frequent in Japan. Mechanism of liver injury has been studied extensively. Alcohol itself is toxic but other factors such as dietary fat are also important. Biochemical and immunological markers of drinking were presented. As for the treatment, most patients especially in early stages of the disease well respond to alcohol withdrawal, but therapy of alcohol dependence in the background of the disease is very difficult requiring cooperative works of different kinds of specialists.
Keywords
alcohol
liver
epidemiology
genetic factors
alcohol dependence
Published Date
1993-01-31
Publication Title
岡山大学医療技術短期大学部紀要
Publication Title Alternative
Bulletin of School of Health Sciences Okayama University
Volume
volume3
Publisher
岡山大学医療技術短期大学部
Publisher Alternative
School of Health Sciences Okayama University
Start Page
1
End Page
12
ISSN
0917-4494
NCID
AN10355371
Content Type
Departmental Bulletin Paper
language
日本語
File Version
publisher
Refereed
False
Eprints Journal Name
fhs