| URI | http://ousar.lib.okayama-u.ac.jp/metadata/17068 |
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| フルテキストURL | 92_629.pdf ( 227.7KB ) 公開日 2010-02-17
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| タイトル | 心拍数と心筋酸素消費量 ―1心拍当りの心筋酸素消費量と心拍数の関係― |
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| タイトル（別表記） | Inverse relationship between heart rate and myocardial oxygen consumption per beat |
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| 著者 | | 著者 | 原岡 昭一 |
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| Author | Haraoka Shoichi |
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| 著者 | 庵谷 和夫 |
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| Author | Ihoriya Kazuo |
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| 著者 | 長花 晴樹 |
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| Author | Nagahana Haruki |
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| 著者 | 藤井 章伸 |
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| Author | Fujii Akinobu |
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| 著者 | 間嶋 行造 |
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| Author | Mashima Ikuzo |
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| 抄録 | Relationship between heart rate and myocardial oxygen consumption per beat was studied in anesthetized open-chest dogs. Myocardial oxygen consumption per minute (MVO(2)) was calculated as the product of the left coronary artery blood flow and coronary arterio-venous oxygen difference. Myocardial oxygen consumption per beat (MVO(2)-Beat) was the quotient of MVO(2) divided by heart rate (HR). HR was varied in 78-210 beats/min with left atrial pacing. Systemic arterial and left ventricular enddiastolic pressure were kept constant, and arterial blood gases were within physiological ranges. Although MVO(2) correlated significantly with HR (r=0.71), MVO(2)-Beat decreased in association with an increase in heart rate. Closer relationship was observed between MVO(2)-Beat and HR; MVO(2)-Beat (ml/100g LV muscle)= -0.00036 + 0.13, r= -0.86, P<0.001. As the results, MVO(2) was represented as a quadratic equation of HR; MVO(2) (ml/min/100g LV muscle)= -0.00036HR(2) + 0.13HR. There was a good correlation (r=0.88) between MVO(2)-Beat and the area under a stroke left ventricular pressure curve. This finding and constant systemic arterial and left ventricular pressure suggest that the inverse relationship between MVO(2)-Beat and HR is mainly due to a reduction in duration of systolic left ventricular wall tension. |
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| キーワード | 心拍数
心筋酸素消費量
左室内圧
収縮時間
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| 発行日 | 1980-06-30 |
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| 出版物タイトル | 岡山医学会雑誌 |
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| 出版物タイトル（別表記） | Journal of Okayama Medical Association |
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| 巻 | 92 |
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| 号 | 5-6 |
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| 出版者 | 岡山医学会 |
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| 出版者（別表記） | Okayama Medical Association |
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| 開始ページ | 629 |
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| 終了ページ | 633 |
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| ISSN | 0030-1558 |
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| NCID | AN00032489 |
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| 資料タイプ | 学術雑誌論文 |
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| オフィシャル URL | http://www.journalarchive.jst.go.jp/japanese/jnlabstract_ja.php?cdjournal=joma1947&cdvol=92&noissue=5-6&startpage=629 |
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| 関連URL | http://www.okayama-u.ac.jp/user/oma/index.html
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| 本文言語 | 日本語
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| OAI-PMH Set | 岡山大学
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| 著作権者 | 岡山医学会 |
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| 論文のバージョン | publisher |
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